Lactobacillus plantarum DR7 -

Alleviates Stress & Anxiety

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Anxiety is a common disorder in our modern lifestyles and can be triggered by stress, aging and obesity.

In 111 stressed adults (DR7 n=56, placebo n=55), the consumption of Lactobacillus plantarum DR7 (1×109 cfu/day) for 12 weeks reduced symptoms of stress (P=0.024), anxiety (P=0.017), and total psychological scores(P=0.022) as early as 8 weeks among stressed adults compared to the placebo group as assessed by the DASS-42 questionnaire. DASS-42 comprises of 42 item self-report validated inventory including three scales designed to measure the negative emotional states of depression, anxiety and stress, where each of the three scales contained 14 questions.

(A)

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(B)

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(C)

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Figure 2: Effects of a 12-week administration of Lactobacillus plantarum DR7 or placebo, on changes in scores as compared to week 0 for (A) Stress, (B) Anxiety, (C) Total scores DASS-42 in all subjects. P-values indicated difference between treatment groups at individual time points. Results are expressed as mean; error bars (SEM); n=111 (DR7 n=56, placebo n=55).

(Chong et al., Beneficial Microbes, 2019)

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