Wellmune® | The First Oral Innate Immunity Trainer

Immune health is at the core of overall wellness. It is no longer just a seasonal concern, but a year-round priority. Consumers today are actively seeking personalised, effective, and convenient ways to support their immune systems, whether caring for their children or maintaining their own health as they age.

This growing demand is reflected in market insights. Innova’s 2023 research found that 70% of parents are drawn to immunity claims on food and beverages, while FMCG Gurus’ 2025 report revealed that 54% of global consumers support immune health through exercise and favour products with added functional benefits backed by scientific validation. (1)

Beyond lifestyle and supplementation, emerging science highlights the body’s natural ability to strengthen itself. Studies show that everyday exposure to foreign pathogens can “train” innate immune cells, enabling them to respond more efficiently to a broad range of health challenges - a process known as trained innate immunity.

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The First Clinically Studied Innate Immunity Trainer

Wellmune® is a patented, proprietary baker’s yeast beta 1,3/1,6 glucan with a unique structure, source, and mechanism of action. It is the first ingredient to be clinically studied as an oral innate immunity trainer, offering a distinctive way to support immunity and everyday health.

Backed by robust clinical evidence, Wellmune® is an ideal immune health ingredient proven to deliver real benefits. 18 clinical studies involving more than 2,300 adults and children demonstrate its ability to:

• Support healthy human immune responses

• Promote overall wellbeing

Importantly, not all beta glucans are created equal. Research shows that only specific structures can influence immune activity, with their effectiveness depending on precise chemical makeup. Wellmune®’s scientifically validated advantages cannot be matched by other beta glucans with different structures.

How Wellmune® Trains the Your Innate Immunity?

When your immune system is trained, innate immune cells develop a short-term memory of pathogens. This helps your immune system respond more effectively to everyday viruses and bacteria without needing prior exposure to the exact threat in order to recognize it.

Innate immune training works much like athletic training. Just as athletes prepare their bodies to perform at their peak on game day, trained innate immune cells return to a resting state after training, ready to leap into action and protect the body against foreign threats when needed.

According to in vitro models, Wellmune® has been shown to train innate immune cells as early as one hour after consumption. Literature suggests that trained immune cells can provide protection lasting 2 - 3 months (2,3). Furthermore, following an unrelated challenge, Wellmune® trained cells responded more rapidly than untrained cells, demonstrating a heightened response within 6 - 12 hours of exposure to a stimulated challenge in vitro.

Wellmune® trains innate immune cells for a rapid, vigorous response (4)

Wellmune® trains innate immune cells to kill foreign threats more efficiently (4)

Wellmune® Innate Immunity Trainer: One of A Kind

Innate immune training is much like fitness training. People of all ages can train to improve their body’s readiness to face daily challenges. Similarly, Wellmune® trains the innate immune system, enhancing its fitness and priming it for a faster, more effective response to everyday health challenges.

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